Psoriasis is a common, chronic, inflammatory, multisystem disease with predominantly skin and joint manifestations. Afflicting people of all ages, psoriasis typically presents before the age of 35. The severity of psoriasis typically ranges from mild to severe, depending on the percentage of affected skin, the physician’s assessment, and the impact on the patient’s life. The most common type is plaque psoriasis, affecting 80% to 90% of psoriasis sufferers. Psoriasis not only causes physical and social discomfort, it can also affect the quality of life of sufferers and their relatives.
Psoriasis is generally believed to have a genetic basis. In patients who are predisposed to psoriasis, environmental factors can trigger its onset. These factors include psychological stress, certain medications, bacterial infection, and skin trauma.
Most patients with psoriasis can be managed by topical treatment, such as corticosteroids, vitamin D analogues, or combination products. Topical treatments come in a variety of formulations such as creams, ointments, solutions, and gels to meet the individual patient’s preferences. Depending on the extent and severity of the disease, other treatment options may include phototherapy with ultraviolet radiation, or systemic therapy in the form of tablets, injections, or infusions.